Young Kwon, Ph.D.

Young is an Operating Partner of LSV. He assists the LSV biopharmaceutical team with deal sourcing, due diligence, and portfolio company management. He has served in this role since April 2021.

Young is an accomplished executive with significant operating and venture capital experience.

He has held a variety of leadership roles over ten years as a C-suite executive at Momenta Pharmaceuticals, a public biotech company, prior to its sale to Johnson & Johnson for $6.5 billion.

Young was most recently Chief Financial and Business Officer at Momenta, where he had responsibility for business development, strategy, finance, investor relations, and commercial. Young has led public equity financings raising nearly $500 million and also led the company’s sale to J&J. Prior to Momenta, Young was a business development professional at Biogen, driving a variety of transactions. Young previously worked at ATV, working with the team on investments including Acceleron, Five Prime, Hypnion, and Zeltiq.

Christina Isacson, Ph.D.

Christina Isacson is a Partner of Lightstone Ventures and focuses on investments in the biopharmaceutical sector. Christina has spent over 15 years in the biotech industry across operational roles and in venture capital. She brings experience in creating, launching, building and operating early stage biotechnology companies including Magenta Therapeutics (NASDAQ:MGTA) and Decibel Therapeutics (NASDAQ:DBTX).

Before joining Lightstone in 2021, Christina was part of the founding team and Chief Business Officer at Magenta Therapeutics where she was accountable for portfolio strategy and management, program management, business development, alliance management and commercial strategy. Prior to Magenta, Christina was Principal at Third Rock Ventures, an early-stage life sciences venture capital firm. At Third Rock, Christina focused on new company formation, due diligence, and led business development efforts more broadly on behalf of Third Rock. Prior to being part of the founding teams of Magenta and Decibel, Christina held operational roles at Ironwood Pharmaceuticals (NASDAQ:IRWD) in corporate development. In addition, she has held venture roles with Boston University’s Technology Development Fund and with Accelerator Corp (Fund I).

Originally trained as a Ph.D. in Neuroscience, leading the integration of science and medicine with business is a fundamental objective in her career.

Doug Treco, Ph.D.

Doug Treco, PhD, was a co-founder of Ra Pharmaceuticals, Inc. in 2008 and served as Chief Executive Officer and a member of the Board of Directors from its inception until its acquisition by UCB in April 2020. Previously, he was an Entrepreneur-in-Residence at Morgenthaler Ventures from January 2008 to May 2014. In 1988, he co-founded Transkaryotic Therapies Inc. (TKT), a multi-platform biopharmaceutical company developing protein and gene therapy products, which was acquired by Shire Pharmaceuticals Group plc in 2005.  Dr. Treco was a Visiting Scientist in the Department of Molecular Biology at Massachusetts General Hospital and a Lecturer in Genetics at Harvard Medical School from 2004 to 2007. He received his Ph.D. in Biochemistry and Molecular Biology from the State University of New York at Stony Brook and performed postdoctoral studies at the Salk Institute for Biological Studies and Massachusetts General Hospital.

Adeline Lin, Ph.D.

Adeline is an associate at Lightstone Singapore PTE. LTD. where she supports the team in evaluating new investment opportunities in the biopharmaceutical and medical device sectors.
Adeline was awarded the National Science Scholarship from the Agency for Science, Technology and Research (A*STAR) and received her B.Sc. from the University of Illinois, Urbana Champaign and her Ph.D. in Microbiology from Washington University, St Louis. Prior to joining Lightstone, Adeline was at A*STAR managing strategic research collaborations with industrial partners in the life sciences sector.

Hong I. Wan, Ph.D.

Hong I. Wan, Ph.D. is president, chief executive officer and co-founder of Tallac Therapeutics. Previously as chief scientific officer and a member of the founding management at ALX Oncology, she led the team to advance ALX148, a best-in-class myeloid checkpoint inhibitor, for multiple tumor indications. Prior to ALX Oncology, Dr. Wan held various leadership positions at Pfizer and Wyeth Research, where she was responsible for the early development and translational medicine strategy and execution across various therapeutic areas. Dr. Wan started her career at Renovis where she led discovery programs in neuroinflammation.

Jaume Pons, Ph.D.

Dr. Pons currently serves as the President and Chief Executive Officer of ALX Oncology. He previously served as Chief Scientific Officer and site head of Rinat (Pfizer), where he was responsible for portfolio delivery from idea to clinical development. He implemented the vision of a company unit following biology across therapeutic areas while generating advanced antibody technologies and turned Rinat into the center of cancer immunology for Pfizer. Dr. Pons is an inventor of fremanezumab, which was approved by the FDA in 2018, as well as two other antibodies in late-stage clinical development and has advanced nine additional antibodies into human trials in multiple therapeutic areas. As Senior Vice President of R&D, he was a member of Pfizer’s World R&D Leadership Team. Before Pfizer, Dr. Pons created and led Rinat’s protein engineering group and was a scientist at Chiron.

Susan Molineaux, Ph.D.

Dr. Molineaux is the co-founder, President and CEO of Calithera Biosciences, a start-up company that commenced operations in June of 2010. Prior to starting Calithera, Dr. Molineaux was a co-founder of Proteolix and served as the CSO for two years before becoming President and CEO of the company. Proteolix was acquired by Onyx Pharmaceuticals in November 2009. Prior to joining Proteolix, Dr. Molineaux was Vice President of Biology at Rigel Pharmaceuticals from 2000 to 2003. Before that, she was Vice President of Biology at Praelux, and from 1994 through 1999, Dr. Molineaux served as Vice President of Drug Development at Praecis Pharmaceuticals. From 1989 until 1994 she was a scientist in the immunology group at Merck, in Rahway, NJ.

Wen Qi Ho, Ph.D.

Wen Qi is a Vice President at Lightstone Singapore Pte,Ltd., where she evaluates new investment opportunities in the biopharmaceutical and medical device sectors out of the firm’s Singapore office.

Wen Qi attained her B.Sc. in Molecular and Cellular Biology at Johns Hopkins University, and her PhD in Immunology at Stanford University under the guidance of Professor Gerald Crabtree, a Howard Hughes Medical Institutes investigator. She was also the recipient of the National Science Scholarship from the Agency for Science, Technology and Research (A*STAR) Singapore. While at Stanford, she enrolled in the Program in Innovation and Entrepreneurship at the Stanford School of Business where she learned business fundamentals and had hands-on experience at developing an idea to business plan. Since moving to Singapore, Wen Qi has been actively involved in the Executive Committee of Biotech Connection Singapore, which aims to promote the life science entrepreneurship eco-system in Singapore by providing a platform for innovators, academics, and investors to come together.

Caroline Gaynor

Caroline joined Lightstone Ventures in 2017 and evaluates new investment opportunities in the biopharmaceutical and medical device sectors out of the firm’s Dublin office.

Caroline has over 10 years’ operational experience in the pharmaceutical industry. Caroline spent 9 years at Bayer Healthcare, most recently serving on the board of senior management of Bayer Ltd. Ireland as head of market access, pricing and reimbursement. During her time in pharma she held a number of operational roles, predominantly focused on oncology, such as product management, strategic marketing, business development and regulatory affairs. Prior to Lightstone, and following completion of her BioInnovate fellowship in 2013, she co-led R&D on a device targeting Acute Pancreatitis and was subsequently involved in early pre-clinical, strategic clinical and commercial development at Vetex Medical..

She currently serves as a director on the board of Catamaran Bio Ltd. and as observer to the board of Carrick Therapeutics, Cerevance, and FIRE-1. She also previously served on the board of ALX Oncology. She is a member of the BioInnovate Ireland Board of advisors.

Kenneth D. Noonan, Ph.D.

Ken is currently the CEO of Lightstone Singapore Pte, Ltd.

Previously Ken was a consultant to the life science industry. Most recently he was a senior partner and head of the European Life Sciences Practice at L.E.K. Consulting LLP. Prior to that he was a partner in the pharmaceutical practice at Booz-Allen & Hamiliton. Ken was also the founding partner and head of the European practice at The Wilkerson Group Ltd. Ken’s operating experience in discovery includes management roles at Cooper Life Sciences (to include Technicon), Becton Dickinson and Bethesda Research Labs.

Ken has served as a Board member of both public and private life science companies in Europe and the U.S. to include Intercept Pharmaceuticals Inc., Kailos Genetics and Orchid Biosciences.

During his academic career Ken authored more than 50 articles on the role of the cell surface in cell division.